Main content

Mela B3 Intense Anti-dark spot serum

NEW anti-hyperpigmentation serum that corrects the appearance of dark spots
LA ROCHE-POSAY MELA B3 SERUM: INTENSE ANTI-DARK SPOT SERUM FOR HYPERPIGMENTATION 30ML is rated 4.5 out of 5 by 1228.
  • y_2026, m_4, d_12, h_10
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.43
  • cp_1, bvpage1
  • co_hasreviews, tv_5, tr_1223
  • loc_en_GB, sid_LRP_181, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_la-rocheposay
  • bvseo_sdk, dw_cartridge, 18.2.0, p_sdk_3.2.0
  • CLOUD, getAggregateRating, 4ms
  • reviews, product
658 people recently viewed this product

A NEW anti-hyperpigmentation serum that corrects the appearance of dark spots, even persistent ones. ... Read more

Mela B3 Intense Anti-dark spot serum

NEW anti-hyperpigmentation serum that corrects the appearance of dark spots

Old price New price £48.00
Receive a free gift when you spend £40 or 2 when you spend £50

Why shop with us?

Free Samples DERMATOLOGIST
RECOMMENDED
Free Delivery Free delivery
over £25
Icon of a smartphone displaying a user profile, indicating facial recognition feature. Virtual Services
PDP Tabs

A NEW anti-hyperpigmentation serum that corrects the appearance of dark spots, even persistent ones. Co-developed with leading dermatologists and pigmentation experts, MELA B3 combines new multi-patented Melasyl™ ingredient - our active melanin trapper - with 10% Niacinamide (also known as Vitamin B3) for a multi-action against hyperpigmentation that also soothes skin & strengthens the skin barrier. Acts to lighten the appearance of existing pigmentation whilst helping prevent the appearance of future dark spot discolouration. Helps even skin’s tone with an ultra-sensorial lightweight gel-serum texture. 

Clinically tested on dark spot prone skin. Dark Spots Clinically Reduced for 94%*

Hyperpigmentation Innovation: new multi-patented Melasyl™ active. Fight Hyperpigmentation. A new mode of action, like never before. Intercepts excess melanin at a different stage of its production before it marks the skin.

*50 subjects, instrumental measurement of size of overall area of dark spots after 12 weeks. 

THE SCIENCE BEHIND

Melanin production: Melasyl™ has a new mode of action compared with referent dermatological actives: it’s an interceptor of melanin precursors. It acts early in the mechanism of melanin synthesis to avoid its overproduction and the appearance of pigmentary concerns in the form of dark spots on the skin.  Clinically tested on all skin tones, our multi-patented Melasyl™ is the result of 18 years of research, selected over 4,000 molecules. Honouring the skin’s natural melanin production, MELA B3 respects the natural beauty of our skin, suitable for all tones and types, including sensitive skin. Alcohol-free, hypoallergenic & non-comedogenic formula, developed with dermatologists. Targets all pigment irregularities even persistent dark spots. Also suitable for those who may be prone to post-acne marks (post-inflammatory hyperpigmentation/ PIH), sun spots and age spots.  Complete formula acts in several ways to reduce the appearance of hyperpigmentation. Active ingredients include: Melasyl™, 10% Niacinamide, Retinol (retinyl palmitate), Hyaluronic Acid & LHA. Our formula gently promotes skin surface renewal & exfoliation for a more radiant look.

KEY BENEFITS

  • Anti-Hyperpigmentation: dark spots, post-acne marks and coloured pigmentation marks appear reduced. 
  • Hydrating formula. Hypoallergenic, alcohol-free. Non comedogenic. Dermatologically tested.
  • New Melasyl™ active ingredient: Fights Hyperpigmentation. A new mode of action, like never before; intercepts excess melanin at a different stage of its production before it marks the skin.
  • Peach-coloured gel-serum formula: light to touch & high skin affinity for fast absorption and no stickiness. 
  • Anti-Post-Acne Marks & PIH (Post-Inflammatory Hyperpigmentation): Fades appearance of stubborn marks and gives a more even skin tone appearance. 
  • Moisturising and soothing action. Also suitable for those who may be prone to pigmentations caused by external factors such as sun, age, post-acne marks.
  • Suitable for sensitive skin. 

ACTIVE INGREDIENTS

NEW MELASYL™ ACTIVE
Fights Hyperpigmentation. A new mode of action, like never before; intercepts excess melanin at a different stage of its production before it marks the skin, helping to prevent the appearance of pigment irregularities. 

NIACINAMIDE (VITAMIN B3)
A dermatological powerhouse, proven to target dark marks and pigmentation. MELA B3 serum helps to visibly fade dark marks including post acne marks and discolorations.

LHA & RETINYL PALMITATE
A powerful yet gentle exfoliating active duo known to boost skin’s surface cell renewal. Skin appears more radiant and even.

SPECIFICALLY FORMULATED FOR

Targets the appearance of all pigment irregularities even persistent dark spots. Also suitable for those who may be prone to post-acne marks (post-inflammatory hyperpigmentation/ PIH), sun spots and age spots.

DERMATOLOGICALLY TESTED

This active serum has been through testing under dermatological control. It is non-comedogenic and is also suitable for use for those who may be prone to pigmentations caused by external factors such as sun, age, post-acne marks. 

                                                                                                                

RECOMMENDED BY DERMATOLOGISTS

La Roche-Posay is the No. 1 Dermatologist recommended brand in the UK** 
**Study of 73 Consultant Dermatologists Jan-April 2023.

Apply 3-4 drops morning and/or evening to face, neck & décolleté after cleansing. Always complete morning routine with daily SPF. 

Ingredients

AQUA / WATER • DIMETHICONE • NIACINAMIDE • GLYCERIN • PROPYLENE GLYCOL • POLYSILICONE- 11 • SILICA • BIS-PEG/PPG-16/16 PEG/PPG-16/16 DIMETHICONE • CYSTOSEIRA TAMARISCIFOLIA EXTRACT • 2-MERCAPTONICOTINOYL GLYCINE • PEG-20 METHYL GLUCOSE SESQUISTEARATE • SODIUM HYALURONATE •SODIUM HYDROXIDE • SODIUM THIOSULFATE • CARNOSINE • POLOXAMER 338 • AMMONIUM POLYACRYLOYLDIMETHYL TAURATE • DIPOTASSIUM GLYCYRRHIZATE • CAPRYLIC/CAPRIC TRIGLYCERIDE • CAPRYLOYL SALICYLIC ACID •CAPRYLYL GLYCOL • CITRIC ACID • TRISODIUM ETHYLENEDIAMINE DISUCCINATE • XANTHAN GUM • PENTYLENE GLYCOL • OCTYLDODECANOL • RETINYL PALMITATE • TOCOPHEROL • PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE • PHENOXYETHANOL​

*Please be aware that ingredient lists for products in our brand are updated regularly. Please refer to the ingredient list on the product package for the most up-to-date list of ingredients to ensure it is suitable for your personal use.

DELIVERY:

Standard Delivery (3-5 working days*)

  • Free for all UK orders over £25**
  • £3.95 for all UK orders below £25**

Standard Delivery (order by 10:30am*)

  • Free for all UK orders over £75***
  • £6.95 for all UK orders below £75**

RETURNS:

If you wish to return your order, you may do so free of charge by filling out our online Contact Us Form. Our returns policy is 28 days.

For more details please refer to our Terms and Conditions.

*Estimated delivery time if order is placed before 11am on a working day for standard delivery, or 10:30am for standard delivery. If order is placed after this time or on any non-working day, then estimated delivery will be on the second working day. Please note that for delivery to Northern Ireland, Scottish Highlands, islands, Aberdeen and other rural areas, an extra working day needs to be taken into account.

**Delivery costs will be displayed on the checkout page of the website.

***until 23:45 on 31.10.2023. Cannot be used in conjunction in with any other code. Valid for one use. One redemption per customer. Offer available at www.LaRoche-Posay.co.uk. Incomplete, illegal, misdirected or late redemptions will not be valid. Promoter is not responsible for redemptions lost, damaged or delayed due to technical or connectivity or other problems. Promoter: LaRoche-Posay.

PDP Get The Look Section
PDP Service Pushes
PDP Product Social Links Mobile
PDP Routine Section
PDP Reviews
Rated 3 out of 5 by from Not made any noticeable difference Bought this on some sort of discount, thankfully, because I would have been cheesed off had I pid full price. Sinks in nicely, fine under make up and other skincare, but that's about it. No change to my post inflammatory hyperpigmentation and I am almost at the end of the second bottle.
Date published: 2026-03-28
Rated 1 out of 5 by from This is not a spots corrector. This was actually my 5th bottle of this Mela B3 serum and I don’t think it does all that they claim. I have been using it since 2025 and my black spots and acne scars are still there. I won’t buy it again.
Date published: 2026-03-28
Rated 4 out of 5 by from Great product I've been using this consistently for a few months along with the cleanser and honestly I can see a real improvement in both my dark spots, hyperpigmentation/melasma. Highly recommend. The price is expensive though. I have brown skin so this is great for melinated skin
Date published: 2026-03-25
Rated 5 out of 5 by from Useful product [This review was collected as part of a promotion.] With consistent use, It has made my complexion even
Date published: 2026-03-17
Rated 1 out of 5 by from Did not work I have been using the mela b for dark spots for nearly a year day and night on face and hands and it has not done anything
Date published: 2026-03-06
Rated 5 out of 5 by from I used for long time. It is five star product. I Good. I am impressed by its result. I have been using for long time.
Date published: 2026-03-02
Rated 2 out of 5 by from Gamel Dos not do the job need la roche posay to do better
Date published: 2026-02-27
Rated 5 out of 5 by from Best serum I used a lot serums before this ,but this works magically .Do recommend to others for sure
Date published: 2026-02-15
  • y_2026, m_4, d_12, h_10
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.43
  • cp_1, bvpage1
  • co_hasreviews, tv_5, tr_1223
  • loc_en_GB, sid_LRP_181, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_la-rocheposay
  • bvseo_sdk, dw_cartridge, 18.2.0, p_sdk_3.2.0
  • CLOUD, getReviews, 3ms
  • reviews, product
PDP Comparison Table
You May Also Like
Orientation message
For the best experience, please turn your device