Toleriane Ultra Overnight Care

Toleriane Ultra Overnight Care is rated 4.4 out of 5 by 86.
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40 ml
An overnight moisturiser for ultra sensitive and intolerant skin
Special Price £13.13 Regular Price £17.50



A Moisturiser for ultra sensitive, intolerant or allergy-prone skin to hydrate and reduce skin sensitivity overnight.


Specifically formulated for every sensitive, reactive skin prone to dryness, tightness, redness, itchiness or burning. A formula proven to soothe, hydrate and reduce skin sensitivity night after night. Suitable for allergy-prone skin

  • For ultra sensitive, reactive or intolerant skin
  • Clinically proven to reduce skin sensitivity, night after night
  • Reduces skin tightness and the appearance of redness


Enriched with neurosensine, niacinamide, carnosine and vitamin A, plus soothing Thermal Spring Water to help skin improve its natural barrier and instantly soothe irritated skin.


Toleriane has been through rigorous dermatological testing to ensure it is suitable for use on even the most sensitive skin. Toleriane is the first skincare range to be given the Seal of Approval by Allergy UK.

9/10 dermatologists would recommend La Roche-Posay for sensitive skin*


The minimalist formula contains the best of our creations – designed for sensitive skin and all of its needs. Tested and re-tested for its efficacy and mildness on sensitive skin. It is also hypoallergenic.

This is a cosmetic product. For medical conditions seek advice from your GP

*Survey of 249 Dermatologists who chose to attend a La Roche-Posay sponsored symposium, July 2016

Free Shipping

on all orders over £25

Free Product Samples

3 included with this purchase

  • Aqua / Water
  • Glycerin
  • Squalane
  • Propanediol
  • Butylene Glycol
  • Butyrospermum Parkii Butter / Shea Butter
  • Pentylene Glycol
  • Niacinamide
  • Dimethicone
  • Ammonium Polyacryldimethyltauramide / Ammonium Polyacryloyldimethyl Taurate
  • Polymethylsilsesquioxane
  • Polysorbate 20
  • Allantoin
  • Glyceryl Acrylate/Acrylic Acid Copolymer
  • Dimethiconol
  • Aluminum Starch Octenylsuccinate
  • Carnosine
  • Disodium EDTA
  • Citric Acid
  • Acetyl Dipeptide-1 Cetyl Ester
  • Xanthan Gum
  • T-Butyl Alcohol
  • Toluene Sulfonic Acid
  • Tocopherol
  • Formula Number 609834 11
  • FIL Number B178893/1
  • Please check back of pack for up to date

Free UK standard delivery on all orders and Free Returns*

Standard Delivery 3-5 working days**

* If order is placed before 11am on a working day. If order is placed after 11am or on any non-working day then estimated delivery will be on the second working day.

**On all orders over £25

Sustainability Commitment

Our planet

The environment, our commitment from source.


Optimum protection. The La Roche-Posay spring water is over 1700 years old. It is protected from any types of pollution after it reaches the surface until it is used for spa therapy purposes.


More recycling. We favour use do recycled raw materials and easily recycled packaging.

Fewer materials. We use cardboard packaging tailored to size to avoid bulky secondary packaging, sourced from 100% sustainably managed forests (FSC - Forest Stewardship Council - certified cardboard).


An ambitious agenda. 100% ISO 14001 certified plants committed to ambitious objectives in the areas of waste management, water saving and reduced CO2 emissions (more than 50% by 2015, compared to 2005).

Renewable energies. 1000 tons of CO2 emissions avoided each year thanks to our geothermal program.


I was a little concerned when I first used this cream, as it has quite a rich texture and I thought it may be too heavy for my oily skin. However, my fears were unfounded as it sinks into the skin beautifully, with no oily residue. Unlike other night creams I've tried, I don't wake up looking horribly shiny! Gorgeous.


Upon waking, skin looks calmed, relieved, and free from discomfort. Skin becomes less sensitive night after night with regular use. Upon application, skin feels immediately relieved, soothed and hydrated. Reduces tightness and the appearance of redness.

  • 86% agree Toleriane Ultra makes the skin look more rested.
  • 76% agree Toleriane Ultra visibily reduces redness.
  • 86% Toleriane Ultra reduces itching sensations.

(*Survey conducted on 54 women, conducted by La Roche-Posay).

Our Brand

Our Brand
For 30 years, we’ve been working in partnership with dermatologists to bring the most efficacious yet highly tolerated products to those with sensitive skin. Whatever your skin concern and whatever your stage in life, La Roche-Posay has a solution – even for those with the most delicate and reactive of skin.

How To

Learn how to use


Apply cleanser using fingertips then carefully wipe off using a cotton disc. Take care not to over wipe.

We recommend



Spray face with spring water to keep skin hydrated and cool.

We recommend



Apply to the face, eye contour and neck every evening.

We recommend



Customer Reviews

Rated 4 out of 5 by from Great, soothing cream I have been using the Toleriane overnight cream sporadically for about 2-3 weeks and have found it to be really good on my skin, especially as I experience sensitivity and breakouts every now and then. I really like the package, easy to take with you if you need and practical and the pump makes it really easy to control the quantity, which you don't really need too much of. It feels really soothing and and calming on my skin and I have seen the difference as, at the same time, I have been using another medicinal cream for acne which dries out the skin (along with helping dry out the pimples). So the Toleriane cream has helped rehydrating and balancing my skin so I would definitely recommend it. The price is a bit high, however, there are products that are even more expensive and don't really do the job. So I think this product is good value for the money.
Date published: 2016-06-07
Rated 1 out of 5 by from Those with Sulphonomide allergies beware! I have very sensitive and menopausal skin and use Toleraine Ultra with no problems, so was delighted to try Toleraine Ultra Nuit, as I often wake up with very dry, irritated and red skin (night sweats don't help). Upon using the Nuit cream, I felt as though the skin on my face was burning and it became very red, tight and sore. The skin on my neck was also blotchy, red, burning, tight and sore and looked as if it was going to blister. On investigation I found that this product contains Sulfonic Acid. As I have an allergy to Sulphonomides (mostly found in certain prescription drugs) this product is most certainly not for me. I should have checked the ingredients more thoroughly before using, so I hope this prevents others from the red faced discomfort I am now enduring. I am also allergic to aloe vera but always check for that, as it is in so,many products for sensitive skin.
Date published: 2016-11-01
Rated 5 out of 5 by from Compares to more expensive products ! I am a BIG fan of my Origins "Drink up intensive" overnight mask, which is more expensive than this La Roche-Posay overnight care. I would say, personally i did not expect much, as i am not usually a LR-P fan as their products are too harsh for my super sensitive skin - even the products labelled as 'sensitive' ... this product has changed my view for the better. I apply a little after cleansing and toning just before bed time, my face feels fresh and super clean / soft in the morning =D this is honestly a great product and i would not hesitate to buy it in future, did not react to my sensitive skin - woo! recommended,
Date published: 2016-05-30
Rated 5 out of 5 by from Great for my sensitive skin! I love La Roche Posay's toleriane range. I had been using the day cream for a while when I discovered the night cream and couldn't wait to buy! Since then both are now part of my daily routine and I've bought again! I get eczema on my face and I find that this is perfect for my sensitive skin, leaving my skin feeling moisturised and refreshed. A little expensive I've noticed that there is often some kind of deal on...
Date published: 2017-04-24
Rated 5 out of 5 by from Calms skin I am suffering from middle aged rosacea. My skin was very uneven, red and blemished. Using this at night has calmed my skin down in only one week. I'm very impressed.
Date published: 2018-10-30
Rated 1 out of 5 by from Broke me out the next day There has to be something this brand uses that my skin hates! I’ve tried so many of their products but this one literally broke me out the next morning! I have combination to oily skin and I’m 24 so thought this range would suit me well. It’s nice to apply the consistency is pleasing but the next day i had spots and even my pores looked bigger and almost like they had gunk in them. I’ve since opted for pretty much all natural skin care and some Korean skin care too which is musch better for my skin type
Date published: 2017-11-16
Rated 5 out of 5 by from Lovely overnight cream I never really use over night creams as I'm mid twenties and haven't really had to but lately I've developed uneven skin tone and slight red rashes over my face. The cream only took two applications to get rid of my skin problems and every morning when I wake up now I look refreshed and ready to tackle the day. The cream itself smells nice and isn't too overpowering, and a little goes a long way to covering your entire face and neck. The feeling the cream leaves on after application is nice, light and soft. I normally suffer from sensitive skin too and I had no bad reactions to this cream either. I highly recommend and love all La Roche posay products the more I use them!
Date published: 2016-05-30
Rated 5 out of 5 by from Fantastic alongside retinol I’ve been using this for a couple of weeks now and it’s amazing. I restarted tretinoin after having a break. I was using gel version ret and it was too harsh for my sensitive skin so attempting the cream version. My skin was reacting to everything. I used cerave moisturising cream and hydrating cleanser. The moisturiser and cleanser are too occuslive for my skin whilst it’s sore from the retinol. They both stung so bad! So I did some research and came across this line. I prefer this night version to other day one due to it being that little bit more moisturising with the ingredients compared to the other one. I use this morning and evening and it’s perfect! no stinging. Sinks into the skin beautifully. has helped combat the dry and red skin from using tretinoin. (I have sensitive skin that’s on the dry side.)
Date published: 2019-05-05
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