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Effaclar H ISO-BIOME Moisturising Cream for Sensitive, Blemish Prone Skin 40ML

Effaclar H Iso-Biome Moisturising Cream for Sensitive, Blemish Prone Skin 40ML is rated 3.3 out of 5 by 70.
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An ultra soothing, richly hydrating moisturiser for sensitive, blemish-prone and weakened skin. S ... Read more

La Roche-Posay

Effaclar H ISO-BIOME Moisturising Cream for Sensitive, Blemish Prone Skin 40ML

Old price £21.50 New price £17.20

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An ultra soothing, richly hydrating moisturiser for sensitive, blemish-prone and weakened skin.

SPECIFICALLY FORMUALTED FOR:

Looking for a soothing, non-drying moisturiser for blemish-prone skin? Effaclar H ISO-BIOME Moisturising Cream is an ultra-soothing, richly hydrating moisturiser for sensitive, blemish-prone skin that feels weak and fragile from over-drying treatment. It is also suitable for those prone to acne and suitable for use alongside prescribed oral isotretinoin.
Formulated for skin which feels weak and fragile from over-drying treatment, making it ideal for daily use.

KEY BENEFITS:

  • Soothes and hydrates sensitive, blemish‑prone skin for up to 48 hours
  • Helps repair and strengthen the skin barrier weakened by over‑drying treatments
  • Reduces skin discomfort and redness associated with dryness
  • Helps imperfections, blemishes, blackheads and marks appear reduced
  • Supports the skin’s microbiome
  • Hypoallergenic, minimalist formula tested on sensitive skin
  • Suitable for acne‑prone skin and for use alongside prescribed oral isotretinoin
  • ACTIVE INGREDIENTS:

    • Vitamin B5 + Squalane + Glycerin
    • Orellana Extract + Procerad
    • Aqua Posae Filiformis, a unique prebiotic biomass from La Roche-Posay

    The formula soothes and calms skin discomfort and reinforces anti-imperfection efficacy, targeting imperfections and marks. With a gentle formula with physiological pH, the product is designed to strengthen the skin barrier and help support microbiome function of the skin.

    After use, skin is immediately intensely soothed and hydrated for 48H. Effaclar H ISO-BIOME Moisturising Cream also helps repair the skin barrier and reduce redness associated with dry skin. Imperfections appear reduced, blemishes appear reduced, blackheads and marks are reduced.

    MINIMALIST HYPO-ALLERGENIC FORMULA:

    The minimalist formula is designed for sensitive skin and its needs. Tested and re-tested for its efficacy and mildness on sensitive skin. The formula is also hypoallergenic.

  1. CLEANSE

    First, cleanse your face to remove impurities. We recommend using La Roche-Posay’s Toleriane Dermo-Cleanser

  2. MOISTURISE

    Next, apply Effaclar H ISO-BIOME Moisturising Cream to your face and neck, applying the product to your face, avoiding the eye area.

  3. SPF

    Finish your skincare routine with a broad-protection SPF to protect against sun damage. We recommend Anthelios UVAIR Daily SPF50+.

Ingredients

2039047 14 - INGREDIENTS: AQUA / WATER / EAU • GLYCERIN • SQUALANE • DIMETHICONE • PANTHENOL • ZEA MAYS STARCH / CORN STARCH • NIACINAMIDE • AMMONIUM POLYACRYLOYLDIMETHYL TAURATE • MYRISTYL MYRISTATE • BIXA ORELLANA SEED EXTRACT • STEARIC ACID • POTASSIUM CETYL PHOSPHATE • GLYCERYL STEARATE SE • SODIUM HYDROXIDE • MYRISTIC ACID • 2-OLEAMIDO-1,3-OCTADECANEDIOL • PALMITIC ACID • HYDROXYACETOPHENONE • CAPRYLOYL GLYCINE • CAPRYLYL GLYCOL • VITREOSCILLA FERMENT • CITRIC ACID • MALTODEXTRIN • XANTHAN GUM • PARFUM / FRAGRANCE. (CODE F.I.L. :N282852/1)

The key active ingredients in Effaclar H ISO-BIOME Moisturising Cream are:

  • Vitamin B5
  • Squalane
  • Glycerin
  • Orellana Extract
  • Procerad
  • Aqua Posae
  • Filiformis

*Please be aware that ingredient lists for products in our brand are updated regularly. Please refer to the ingredient list on the product package for the most up-to-date list of ingredients to ensure it is suitable for your personal use.

DELIVERY:

Standard Delivery (3-5 working days*)

  • Free for all UK orders over £25**
  • £3.95 for all UK orders below £25**

RETURNS:

If you wish to return your order, you may do so free of charge by filling out our online Contact Us Form. Our returns policy is 28 days.

For more details please refer to our Terms and Conditions.

*Estimated delivery time if order is placed before 11am on a working day for standard delivery, or 10:30am for standard delivery. If order is placed after this time or on any non-working day, then estimated delivery will be on the second working day. Please note that for delivery to Northern Ireland, Scottish Highlands, islands, Aberdeen and other rural areas, an extra working day needs to be taken into account.

**Delivery costs will be displayed on the checkout page of the website.

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PDP Reviews
Rated 5 out of 5 by from Happy skin I bought this about six weeks ago after a recommendation from a dermatologist. I am 38 years old and had been using a daily tretinoin prescription for around 18 months. I have suffered from acne in the past and I am still prone to hormonal break outs, even when I was using tretinoin. My skin had become very dry and irritated from the tret and I made the decision to stop using it completely and focus on repairing my skin barrier instead. I was worried about using this because some reviews said it could cause acne. This may have been the experience others have had but the opposite is true for me. My skin is the happiest it has been ever, I think. Very calm, nicely hydrated and smooth and even my usual hormonal spots have been kept at bay. Definitely worth a try if you have the same concerns.
Date published: 2026-05-13
Rated 4 out of 5 by from Good for reactive perimenopausal skin! This is a really good moisturiser that helped calm my skin after an allergic reaction. It soothed the irritation and made my skin feel comfortable again without any heaviness. As a woman over 40 who is perimenopausal and still prone to blemishes, I find this cream works extremely well. It provides deep hydration without encouraging oiliness and has actually helped improve my blemishes rather than making them worse. My skin feels balanced, nourished, and calm. I would definitely recommend this moisturiser to anyone dealing with sensitive, reactive skin while still needing effective hydration and blemish control.
Date published: 2026-01-23
Rated 5 out of 5 by from Very good Very good [This review was collected as part of a promotion.] Very good i like it i buy it again text time .Very good i like it i buy it again text time
Date published: 2026-01-04
Rated 5 out of 5 by from Effacular H moisturiser Fantastic moisturiser. Best one I've ever used. Been using for years and now got my teenage children on to it. Love it!
Date published: 2025-11-27
Rated 1 out of 5 by from Caused redness/irritation Caused redness when applied, irritation reaction (red patches) for more than a day now. This is apparently a cream for oily or blemish-prone skin that's been "fragilised" by drying acne treatments; however, it has made my skin even more dry/compromised than before. Creams work different on everyone but this cream just didn't work on me.
Date published: 2025-11-05
Rated 5 out of 5 by from The best moisturiser I’ve ever used. I have blemish prone skin, and a lot of acne scars. This moisturiser has reduced the appearance of my blemishes, and also leaves my skin feeling moisturised for hours without feeling oily or thick. It makes my skin look so shiny!
Date published: 2025-09-23
Rated 3 out of 5 by from Standard face cream Quite basic face cream i ve biught it because supposedly its not comedogenic as most face creams are for my face
Date published: 2025-08-11
Rated 5 out of 5 by from Teenage Triumph A perfect introduction to young teenage skin. Recommended by Dermatologists, this product is just what an impressionable teenage girl needs. If you are prone to monthly outbreaks and sensitivity, this product is gentle yet effective.
Date published: 2025-04-16
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