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Mela B3 Intense Anti-dark spot serum

NEW anti-hyperpigmentation serum that corrects the appearance of dark spots
LA ROCHE-POSAY MELA B3 SERUM: INTENSE ANTI-DARK SPOT SERUM FOR HYPERPIGMENTATION 30ML is rated 4.5 out of 5 by 1234.
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NEW anti-hyperpigmentation serum that helps correct the appearance of persistent dark spots.   ... Read more

Mela B3 Intense Anti-dark spot serum

NEW anti-hyperpigmentation serum that corrects the appearance of dark spots

Old price New price £48.00
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NEW anti-hyperpigmentation serum that helps correct the appearance of persistent dark spots.

 

SPECIFICALLY FORMULATED FOR:

Do you want to reduce the appearance of dark spots and hyperpigmentation? Mela B3 Intense Anti-dark spot serum is our NEW anti-hyperpigmentation serum that corrects the appearance of dark spots – even persistent ones.
Co-developed with leading dermatologists and pigmentation experts, MELA B3 combines new multi-patented Melasyl™ ingredient - our active melanin trapper - with 10% Niacinamide (also known as Vitamin B3) for a multi-action against hyperpigmentation that also soothes skin and strengthens the skin barrier.
It acts to lighten the appearance of existing pigmentation whilst helping prevent the appearance of future dark spot discolouration, making it the ideal choice for people with hyperpigmentation. Helps even skin’s tone with an ultra-sensorial lightweight gel-serum texture.
This product is ideal for targeting the following skin concerns:

  • Dark spots
  •  
  • Persistent pigmentation
  •  
  • Post-acne marks (PIH)
  •  
  • Sun spots
  •  
  • Age spots
  •  
  • Dull, uneven skin tone
  •  
  • Discolouration caused by external factors such as sun exposure or blemishes
  •   Clinically tested on dark spot prone skin. Dark Spots Clinically Reduced for 94%*

KEY BENEFITS

  • Anti-Hyperpigmentation: dark spots, post-acne marks and coloured pigmentation marks appear reduced. 
  • Hydrating formula. Hypoallergenic, alcohol-free. Non comedogenic. Dermatologically tested.
  • New Melasyl™ active ingredient: Makes use of a new Hyperpigmentation innovation thanks to the multi-patented Melasyl™ active, which fights Hyperpigmentation like never before. Melasyl™ active Intercepts excess melanin at a different stage of its production before it marks the skin.  
  • Peach-coloured gel-serum formula: light to touch & high skin affinity for fast absorption and no stickiness, making it ideal for everyday use  
  • Anti-Post-Acne Marks & PIH (Post-Inflammatory Hyperpigmentation): Fades appearance of stubborn marks and gives a more even skin tone appearance. 
  • Moisturising and soothing action. Also suitable for those who may be prone to pigmentations caused by external factors such as sun, age, post-acne marks.
  • Suitable for sensitive skin. 

THE SCIENCE BEHIND

Looking for a cream that helps hyperpigmentation? Melanin production: Melasyl™ has a new mode of action compared with referent dermatological actives: it’s an interceptor of melanin precursors. It acts early in the mechanism of melanin synthesis to avoid its overproduction and the appearance of pigmentary concerns in the form of dark spots on the skin.  Clinically tested on all skin tones, our multi-patented Melasyl™ is the result of 18 years of research, selected over 4,000 molecules. Honouring the skin’s natural melanin production, MELA B3 respects the natural beauty of our skin, suitable for all tones and types, including sensitive skin. It has an alcohol-free, hypoallergenic & non-comedogenic formula, developed with dermatologists.   Melasyl™ targets all pigment irregularities even persistent dark spots. It is also suitable for those who may be prone to post-acne marks (post-inflammatory hyperpigmentation/ PIH), sun spots and age spots.  The complete formula acts in several ways to reduce the appearance of hyperpigmentation. Active ingredients include: Melasyl™, 10% Niacinamide, Retinol (retinyl palmitate), Hyaluronic Acid & LHA. Our formula gently promotes skin surface renewal & exfoliation for a more radiant look.

ACTIVE INGREDIENTS

NEW MELASYL™ ACTIVE
Fights Hyperpigmentation. A new mode of action, like never before; intercepts excess melanin at a different stage of its production before it marks the skin, helping to prevent the appearance of pigment irregularities. 

NIACINAMIDE (VITAMIN B3)
A dermatological powerhouse, proven to target dark marks and pigmentation. MELA B3 serum helps to visibly fade dark marks including post acne marks and discolorations.

LHA & RETINYL PALMITATE
A powerful yet gentle exfoliating active duo known to boost skin’s surface cell renewal. Skin appears more radiant and even.

DERMATOLOGICALLY TESTED

This active serum has been through testing under dermatological control. It is non-comedogenic and is also suitable for use for those who may be prone to pigmentations caused by external factors such as sun, age, post-acne marks. 

RECOMMENDED BY DERMATOLOGISTS

La Roche-Posay is the No. 1 Dermatologist recommended brand in the UK** 
**Study of 73 Consultant Dermatologists Jan-April 2023.

01. CLEANSE
First, cleanse your face. We recommend using Toleriane Dermo Cleanser.

02. APPLY MELA B3 INTENSE ANTI-DARK SPOT SERUM
Then, apply 3-4 drops morning and/or evening to the face, neck and décolleté.

03. ALWAYS USE A BROAD-SPECTRUM SPF DAILY
Finish your skincare routine with an SPF protective cream, like Anthelios UVMune 400. This will help prevent sun damage and dark spots.

Ingredients

AQUA / WATER • DIMETHICONE • NIACINAMIDE • GLYCERIN • PROPYLENE GLYCOL • POLYSILICONE- 11 • SILICA • BIS-PEG/PPG-16/16 PEG/PPG-16/16 DIMETHICONE • CYSTOSEIRA TAMARISCIFOLIA EXTRACT • 2-MERCAPTONICOTINOYL GLYCINE • PEG-20 METHYL GLUCOSE SESQUISTEARATE • SODIUM HYALURONATE •SODIUM HYDROXIDE • SODIUM THIOSULFATE • CARNOSINE • POLOXAMER 338 • AMMONIUM POLYACRYLOYLDIMETHYL TAURATE • DIPOTASSIUM GLYCYRRHIZATE • CAPRYLIC/CAPRIC TRIGLYCERIDE • CAPRYLOYL SALICYLIC ACID •CAPRYLYL GLYCOL • CITRIC ACID • TRISODIUM ETHYLENEDIAMINE DISUCCINATE • XANTHAN GUM • PENTYLENE GLYCOL • OCTYLDODECANOL • RETINYL PALMITATE • TOCOPHEROL • PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE • PHENOXYETHANOL​ 

The key active ingredients in Mela B3 Intense Anti-Dark Spot Serum:

  • New Melasyl™ Active
  • Niacinamide
  • LHA and Retinyl Palmitate

*Please be aware that ingredient lists for products in our brand are updated regularly. Please refer to the ingredient list on the product package for the most up-to-date list of ingredients to ensure it is suitable for your personal use.

DELIVERY:

Standard Delivery (3-5 working days*)

  • Free for all UK orders over £25**
  • £3.95 for all UK orders below £25**

RETURNS:

If you wish to return your order, you may do so free of charge by filling out our online Contact Us Form. Our returns policy is 28 days.

For more details please refer to our Terms and Conditions.

*Estimated delivery time if order is placed before 11am on a working day for standard delivery, or 10:30am for standard delivery. If order is placed after this time or on any non-working day, then estimated delivery will be on the second working day. Please note that for delivery to Northern Ireland, Scottish Highlands, islands, Aberdeen and other rural areas, an extra working day needs to be taken into account.

**Delivery costs will be displayed on the checkout page of the website.

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PDP Reviews
Rated 5 out of 5 by from Love the mela b3 serum So I’ve have been selected to try this product and I love the results so far
Date published: 2026-05-09
Rated 5 out of 5 by from It really works I have quite dry skin, so I was a bit worried this serum might feel harsh, but it’s actually been really comfortable to use. The MELA B3 INTENSE ANTI-DARK SPOT SERUM feels lightweight. It gives hydrating, and it leaves my skin looking brighter and smoother without making it feel tight or irritated. After a few weeks, I noticed some of my dark spots starting to fade and my overall complexion looking more even. I also love that it layers well under a rich moisturiser without pilling.
Date published: 2026-05-08
Rated 5 out of 5 by from Perfect pigmentation reduction I have used this product on and off for a few years especially in the summer.it has helped lighten a few far spots I have on my face.It does not irritate my skin or cause any distress to it.Lightens gradually
Date published: 2026-05-06
Rated 5 out of 5 by from Love this serum Currently one of my fav from la roche po say i love their products this serum is always in my vanity helps my skin so much reduce my dark spot in just few weeks
Date published: 2026-05-05
Rated 4 out of 5 by from Hopefully will do as it says, too early to tell. Too early to tell yet, it’d the product will reduce dark skin spots, but it is easy to apply.
Date published: 2026-05-01
Rated 2 out of 5 by from Not working for me I have been using this product for at least two months now, twice daily and following all instructions. I’m very disappointed to discover that there has been zero reduction in the 2 dark spots on my face, especially as the product has received so much hype and is not cheap.
Date published: 2026-04-21
Rated 3 out of 5 by from Not made any noticeable difference Bought this on some sort of discount, thankfully, because I would have been cheesed off had I pid full price. Sinks in nicely, fine under make up and other skincare, but that's about it. No change to my post inflammatory hyperpigmentation and I am almost at the end of the second bottle.
Date published: 2026-03-28
Rated 1 out of 5 by from This is not a spots corrector. This was actually my 5th bottle of this Mela B3 serum and I don’t think it does all that they claim. I have been using it since 2025 and my black spots and acne scars are still there. I won’t buy it again.
Date published: 2026-03-28
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